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The US Leader in Stem Cell Therapy, Now in Mexico. Affordable treatments start at $3750 for 25 million stem cells!

Special Promo: Get an additional 25 BILLION Exosomes IV with treatments over 50 million cells!”

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Ankylosing Spondylitis

Stem Cell Therapy for Ankylosing Spondylitis in Mexico

What is Ankylosing Spondylitis?

  • It’s a rare type of arthritis also known as Bechterew disease.
  • Usually starts in lower back, may affect neck too.
  • Ankylosis = fused bones/tissue
  • Spondylitis = inflammation in spine
  • Hallmark feature is the involvement of the sacroiliac (SI) joints during the progression of the disease.
  • Unfortunately – can affect other areas of the body such as shoulders, hips, knees, heels, hands – eyes, lungs, heart too!

R3 Stem Cell Guide for Ankylosing Spondylitis

Every day, R3 Stem Cell receives inquiries worldwide from individuals asking if stem cell therapy can help with Ankylosing Spondylitis (AS). Spoiler alert: . . .

Download Free Guide

Diagnosing AS 

  • Pain starts before the age of about 35 – 45.
  • It starts and gets worse gradually.
  • It lasts for at least 3 months.
  • The pain is linked with morning stiffness that usually lasts for more than 1 hour.
  • The pain improves with exercise.
  • The clearest sign of the disease is a change in the sacroiliac joints at the base of the low back.
  • Family member affected?
  • X-rays – bony erosions/fusion/calcification
  • Blood Tests
  • CRP/Sed Rate
  • RF negative – which is why it’s called seronegative spndylarthropathy
  • HLA B27 – 5%

Playlist

2 Videos
Healthcare professional examining patient’s shoulder—representing conventional therapies for ankylosing spondylitis including NSAIDs, PT, and biologics

Conventional Treatment Options for AS

  • First-line therapy
  • NSAIDS
  • Exercise, PT
  • Together, these treatments can lead to substantial clinical improvement in 70-80% of patients.
  • Hallmark feature is the involvement of the sacroiliac (SI) joints during the progression of the disease.
  • Local steroid injection and DMARDs (sulfasalazine and methotrexate) can also help with peripheral manifestations.
  • Second-line therapy includes TNF-alpha blockers (etanercept, infliximab, adalimumab, certolizumab, golimumab) and IL17 inhibitors (secukinumab) and/or narcotics.

Stem Cell Therapy for AS –  How Do Stem Cell Biologics Work? 

  • Paracrine Signaling
  • Recruitment of cells, neovascularization, reduced neuron death.
  • Neovascularization
  • Immunomodulation
  • Direct mechanisms

Mesenchymal stem cells (MSCs) with considerable immunomodulatory and regenerative properties could be able to attenuate the inflammatory responses and help tissue repair by cell-to-cell contact and secretion of soluble factors. 

Scientist transferring liquid in lab—representing how mesenchymal stem cells modulate inflammation and promote tissue repair in AS treatment

Study #1 in the video: 

MSC infusion in AS patients is a safe and beneficial choice with no severe side effects, and is effective in decreasing the related clinical symptoms and severity of the disease 

  • 5 month study
  • four IV infusions of MSCs on days 0, 7, 14, and 21. 
  • 1 million stem cells/kg
  • 31 patients
  • Patient symptoms dramatically improved
  • CRP and ESR decreased
  • Reduction of inflammation by MRI.
  • Theories – migration of MSC to inflammation. Reduction of inflammation by cell-cell contact.

Study #2 – Bone Marrow Stem Cells May be a Problem 

grafts of normal autologous or allogeneic BM-MCS might become one of the best solutions to treat various inflammatory rheumatisms, a small subset of subchondral BM-MSCs could on the opposite be an underrated issue.  Abnormal behaviour of BM-MSCs and/or their progeny has been found in RA, SpA, and AS NOT seen in UC MSCs. 

Conclusion 

Many small studies, early clinical trials and our own experience show that stem cell therapy for AS is not only safe, but typically very effective. 

 

Key Point:

  • Appears that high stem cell numbers are necessary.
  • Combo is what we’ve seen to work best: IV and Injxn
  • UC-MSCs give great results, just like autologous.
  • Embryonic stem cell therapy and IPSC therapy are NOT ready for prime time use by a long shot.
  • Run away if anyone suggests those types of stem cell treatment.
  • Stem Cell Therapy with MSC’s and HSC’s are the way to go.
  • R3 Stem Cell International Treatment Program
  • Performed in Tijuana, Mexico or Mexicali. 20 minutes from SD Airport.
  • Process starts with a free phone consultation – licensed, experienced stem cell doctor.
  • Patient concierge rep assists with all travel logistics including travel from airport to clinic and back.

R3 Stem Cell International Treatment Program 

The cells 

  • GenCell is the lab in Mexico City. Pristine safety record.
  • QA more stringent than FDA.
  • Umbilical cord stem cells are cx, no preservative needed.
  • 95% viability.
  • Pure, potent cells below 5th generation.

The Response To Our Mexico Stem Cell Programs Have Been OVERWHELMING!

Make Sure To Reserve Your Spot Now By Calling Us At  (888) 988-0515.

Our Experienced Providers Will Perform A Free Phone Consultation To See If You Are A Candidate.

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About R3 Stem Cell Mexico

R3 Stem Cell is a global leader in regenerative medicine, offering advanced stem cell and exosome therapies through Centers of Excellence in over 45 locations across 7 countries. Our mission is to provide first-rate, customized regenerative treatments, including stem cells, exosomes, PRP, vitamins, and peptides, to help patients achieve a better quality of life. With more than 26,000 procedures performed and an 85% patient satisfaction rate, our experienced, compassionate providers are committed to delivering safe, effective care. All therapies are nonsteroidal, outpatient procedures designed to harness the body’s natural repair mechanisms and support tissue regeneration. Individual results may vary, and only your medical professional can explain all the risks and potential benefits of any therapy based on your unique circumstances.
 

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Stem cell therapy is considered experimental and is regulated by the U.S. Food and Drug Administration (FDA), but it is not FDA-approved. R3 Stem Cell does not offer stem cell therapy as a cure for any medical condition. No statements made on this site have been evaluated or approved by the FDA. This site does not provide medical advice. All content is for informational purposes only and is not a substitute for professional medical consultation, diagnosis, or treatment. Reliance on any information provided by R3 Stem Cell, its employees, others appearing on this website at the invitation of R3 Stem Cell, or other visitors to the website is solely at your own risk. R3 Stem Cell does not recommend or endorse any specific tests, products, procedures, opinions, or other information that may be mentioned on this website. R3 Stem Cell is not responsible for the outcome of your procedure. The FDA considers stem cell therapy experimental at this point.

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