How does PRP work for hair restoration?
Written by Dr. David Greene, MD, PhD, MBA on September 15, 2025
Written by Dr. David Greene, MD, PhD, MBA on September 15, 2025
Recent scientific research and technology support an innovative new proactive therapeutic treatment for hair restoration using platelet-rich plasma (PRP). When dealing with thinning hair or hair loss due to a medical condition, many patients may turn to pills, pungent creams, stimulatory devices, alternative medicine, and even invasive surgical corrective procedures. Many are unsuccessful and can only offer false hope. PRP may be the nonsurgical answer for men or women who require hair growth stimulation to counteract hair loss.
With research into the processes of wound and tissue healing, the medical community launched scientific studies. Using the all-natural PRP for hair loss treatment as a successful tool for hair loss or conditions causing hair loss and hair thinning was a result of these studies supporting the clinical applications published in Dermatologic Surgery.
Although not meant as a replacement for FDA therapies like DHT blockers or Minoxidil, platelet rich plasma has been used successfully in many fields and demonstrates the potential to be highly effective as a promising treatment for patients with hair loss.
Tissue regeneration and beneficial healing are intensified with platelet rich plasma as it is a concentrated cocktail of mesenchymal stem cells and autologous blood components containing vital proteins and specific growth factors.
PRP is used in many fields including oral surgery, neurosurgery, plastic and cosmetic surgery, and more recently sports medicine and orthopedics after published studies from Europe and the United States confirmed PRP as effective medical treatment.
The ideal hair restoration candidates for PRP treatments are patients with newly thinning hair (such as cancer patients), and Propecia patients who need an alternative treatment due to adverse side effects or complications.
The patient’s blood is drawn spun in a centrifuge unit to develop the concentration of platelets in the platelet rich plasma injection. The platelets contain many intracellular structures, including growth factors, clotting factors, lysosomes, and specific cells to induce hair growth.
Platelet-Derived Growth Factor (PDGF)—for the promotion of blood vessel growth, cell replication, skin formation
Transforming Growth-Factor-Beta (TGF-b)— for the promotion of growth of matrix between cells, bone metabolism
Vascular Endothelial Growth Factor (VEGF)— for the promotion of blood vessel formation
Epidermal Growth Factor (EGF)— for the promotion of cell growth and differentiation, blood vessel formation, collagen formation
Fibroblast Growth Factor-2 (FGF-2)— for the promotion of growth of specialized cells and blood vessel formation
Insulin Like Growth Factor – (IGF)—a regulator of normal physiology in nearly every type of cell in the body Source of specific cells: Role of Platelet-rich Plasma in the Management of Androgenetic Alopecia. Int J Trichology. 2012 Oct-Dec; 4(4): 291–292.
When the centrifuge process is complete, the patient is placed under a topical anesthesia and a specialized device with micro needles is applied to the dermis of the scalp for focused stimulation of the area destined for treatment. The trauma induced in the scalp starts the organic process of natural healing and growth repair of the body. The physician then injects the therapeutic PRP concentration directly into the site to stimulate growth in the hair follicle.
PRP is an all-natural therapy treatment that can be used pre-operatively, intra-operatively, or post-operatively. Research shows regular application of the platelet rich plasma has the best results stimulating hair growth. Patients may choose to have platelet rich plasma injections semiannually or quarterly.
Physician First Choice offers PRP for hair loss which works extremely well for those who would like help. The treatments take a few sessions and typically negate the need for hair transplants. Call (888) 988-0515 for more information and scheduling today!
Contact US